AMPD1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70971
Background:
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alternative Name:
AMP deaminase 1, AMP deaminase isoform M, Myoadenylate deaminase
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100
Specificity: AMPD1 polyclonal antibody detects endogenous levels of AMPD1 protein.
Immunogen:
A synthetic peptide of human AMPD1.
MW: ~ 90 kDa
Swis Prot.: P23109
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alternative Name:
AMP deaminase 1, AMP deaminase isoform M, Myoadenylate deaminase
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100
Specificity: AMPD1 polyclonal antibody detects endogenous levels of AMPD1 protein.
Immunogen:
A synthetic peptide of human AMPD1.
MW: ~ 90 kDa
Swis Prot.: P23109
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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