Annexin 5 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS6525
Background:
Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. For example, the crystal structure of Annexin III has suggested a hydrophilic amino-terminus with possible Ca2+ channel activity. Similarly, Annexin V has ion channel properties. Annexin IV, also referred to as endonexin, functions to regulate Cl-flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity. Annexin V is ubiquitously expressed at high levels in tissues and cells grown in tissue culture, while Annexin VIII exhibits a more limited distribution. Where co-expressed in the same tissues, Annexin VIII is often expressed at a 100-fold lower level than Annexin V. However, Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells, which may relate to its role in hematopoietic cell differentiation.
Alternative Name:
Anchorin CII antibodyAnnexin 5 antibodyAnnexin A5 antibodyAnnexin V antibodyAnnexin-5 antibodyAnnexin5 antibodyAnnexinA5 antibodyAnnexinV antibodyANX 5 antibodyANX A5 antibodyANX5 antibodyANXA5 antibodyANXA5 antibodyCalphobindin I antibodyCBP I antibodyCBP-I antibodyEndonexin II antibodyENX 2 antibodyENX2 antibodyLipocortin V antibodyPAP I antibodyPAP-I antibodyPlacental anticoagulant protein 4 antibodyPlacental anticoagulant protein I antibodyPP 4 antibodyPP4 antibodyThromboplastin inhibi
Application Dilution: WB: 1:500 - 1:2000
Specificity: ANXA5 polyclonal antibody detects endogenous levels of ANXA5 protein.
Immunogen:
Recombinant full length Human Annexin 5.
MW: ~ 36 kDa
Swis Prot.: P08758
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. For example, the crystal structure of Annexin III has suggested a hydrophilic amino-terminus with possible Ca2+ channel activity. Similarly, Annexin V has ion channel properties. Annexin IV, also referred to as endonexin, functions to regulate Cl-flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity. Annexin V is ubiquitously expressed at high levels in tissues and cells grown in tissue culture, while Annexin VIII exhibits a more limited distribution. Where co-expressed in the same tissues, Annexin VIII is often expressed at a 100-fold lower level than Annexin V. However, Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells, which may relate to its role in hematopoietic cell differentiation.
Alternative Name:
Anchorin CII antibodyAnnexin 5 antibodyAnnexin A5 antibodyAnnexin V antibodyAnnexin-5 antibodyAnnexin5 antibodyAnnexinA5 antibodyAnnexinV antibodyANX 5 antibodyANX A5 antibodyANX5 antibodyANXA5 antibodyANXA5 antibodyCalphobindin I antibodyCBP I antibodyCBP-I antibodyEndonexin II antibodyENX 2 antibodyENX2 antibodyLipocortin V antibodyPAP I antibodyPAP-I antibodyPlacental anticoagulant protein 4 antibodyPlacental anticoagulant protein I antibodyPP 4 antibodyPP4 antibodyThromboplastin inhibi
Application Dilution: WB: 1:500 - 1:2000
Specificity: ANXA5 polyclonal antibody detects endogenous levels of ANXA5 protein.
Immunogen:
Recombinant full length Human Annexin 5.
MW: ~ 36 kDa
Swis Prot.: P08758
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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