APC Anti-Human CD184/CXCR4 Antibody [clone 12G5]
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In stock
SKU
E-AB-F1157E
Catalog Number: E-AB-F1157E
Reactivity: Human, Clone: 12G5
Isotype: Mouse IgG2a, κ, Conjugation: APC
Applications: FCM
Datasheet, Questions? Contact us!
Reactivity: Human, Clone: 12G5
Isotype: Mouse IgG2a, κ, Conjugation: APC
Applications: FCM
Datasheet, Questions? Contact us!
Background:
CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.
Research Area: Cancer, Metabolism, Immunology, Microbiology, Neuroscience, Stem cells
Synonyms:
FB22, Fusin, HM89, LCR1, LAP-3
Swissprot: P61073
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Alternative for product with catalog number:
306509, 306510
CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.
Research Area: Cancer, Metabolism, Immunology, Microbiology, Neuroscience, Stem cells
Synonyms:
FB22, Fusin, HM89, LCR1, LAP-3
Swissprot: P61073
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Alternative for product with catalog number:
306509, 306510
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