ARG2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8153
Background:
Arginase I (also designated liver-type arginase), which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster . Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location . Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein . In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence .
Alternative Name:
Arginase-2, mitochondrial, Kidney-type arginase, Non-hepatic arginase, Type II arginase, ARG2
Application Dilution: WB: 1:500 - 1:2000
Specificity: ARG2 polyclonal antibody detects endogenous levels of ARG2 protein.
Immunogen:
Recombinant full length Human ARG2.
MW: ~ 39 kDa
Swis Prot.: P78540
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Arginase I (also designated liver-type arginase), which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster . Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location . Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein . In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence .
Alternative Name:
Arginase-2, mitochondrial, Kidney-type arginase, Non-hepatic arginase, Type II arginase, ARG2
Application Dilution: WB: 1:500 - 1:2000
Specificity: ARG2 polyclonal antibody detects endogenous levels of ARG2 protein.
Immunogen:
Recombinant full length Human ARG2.
MW: ~ 39 kDa
Swis Prot.: P78540
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review