ARHGAP20 polyclonal, anti-human, rat
€305.00
In stock
SKU
BS60766
Background:
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP20 (Rho GTPase activating protein 20), also known as KIAA1391, is a 1,191 amino acid protein that contains one PH domain, one Ras-associating domain and one Rho-GAP domain. Expressed primarily in brain, but also present in lymph nodes and fetal liver, ARHGAP20 functions as a GTPase-activating protein for Rho-type GTPases, effectively converting Rho-type GTPases to an inactive, GDP-bound state. ARHGAP20 exists as multiple isoforms that are produced via alternative splicing. Chromosomal aberrations involving the ARHGAP20 gene are thought to be a cause of B-cell chronic lymphocytic leukemia (B-CLL).
Alternative Name:
Rho GTPase-activating protein 20, Rho-type GTPase-activating protein 20, ARHGAP20, KIAA1391
Application Dilution: WB: 1:500~1:1000
Specificity: ARHGAP20 polyclonal antibody detects endogenous levels of ARHGAP20 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ARHGAP20
MW: ~ 133 kDa
Swis Prot.: Q9P2F6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP20 (Rho GTPase activating protein 20), also known as KIAA1391, is a 1,191 amino acid protein that contains one PH domain, one Ras-associating domain and one Rho-GAP domain. Expressed primarily in brain, but also present in lymph nodes and fetal liver, ARHGAP20 functions as a GTPase-activating protein for Rho-type GTPases, effectively converting Rho-type GTPases to an inactive, GDP-bound state. ARHGAP20 exists as multiple isoforms that are produced via alternative splicing. Chromosomal aberrations involving the ARHGAP20 gene are thought to be a cause of B-cell chronic lymphocytic leukemia (B-CLL).
Alternative Name:
Rho GTPase-activating protein 20, Rho-type GTPase-activating protein 20, ARHGAP20, KIAA1391
Application Dilution: WB: 1:500~1:1000
Specificity: ARHGAP20 polyclonal antibody detects endogenous levels of ARHGAP20 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ARHGAP20
MW: ~ 133 kDa
Swis Prot.: Q9P2F6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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