ARHGEF11 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71014
Background:
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Alternative Name:
GTRAP48, PDZ-RHOGEF,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: ARHGEF11 polyclonal antibody detects endogenous levels of ARHGEF11 protein.
Immunogen:
A synthetic peptide of human ARHGEF11.
MW: ~ 168 kDa
Swis Prot.: O15085
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Alternative Name:
GTRAP48, PDZ-RHOGEF,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: ARHGEF11 polyclonal antibody detects endogenous levels of ARHGEF11 protein.
Immunogen:
A synthetic peptide of human ARHGEF11.
MW: ~ 168 kDa
Swis Prot.: O15085
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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