ARHGEF9 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61256
Background:
ARHGEF9 (Rho guanine nucleotide exchange factor 9), also known as PEM-2 homolog or Collybistin, is a 516 amino acid cytoplasmic protein. ARHGEF9 acts as a guanine nucleotide exchange factor for Cdc42 and promotes formation of Gephyrin clusters by directly interacting with Gephyrin. ARHGEF9 contains one DH (DBL-homology) domain, one PH domain and one SH3 domain. Defects in the gene encoding ARHGEF9 are a believed to be a cause for startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. This disease is a heterogenous neurological disorder characterized by muscular rigidity, particularly in the neonatal period, and a startle response to auditory or tactile stimuli.
Alternative Name:
Rho guanine nucleotide exchange factor 9, Collybistin, PEM-2 homolog, Rac/Cdc42 guanine nucleotide exchange factor 9, ARHGEF9, ARHDH9, KIAA0424
Application Dilution: WB: 1:500~1:1000
Specificity: ARHGEF9 polyclonal antibody detects endogenous levels of ARHGEF9 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ARHGEF9.
MW: ~ 54 kDa
Swis Prot.: O43307
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
ARHGEF9 (Rho guanine nucleotide exchange factor 9), also known as PEM-2 homolog or Collybistin, is a 516 amino acid cytoplasmic protein. ARHGEF9 acts as a guanine nucleotide exchange factor for Cdc42 and promotes formation of Gephyrin clusters by directly interacting with Gephyrin. ARHGEF9 contains one DH (DBL-homology) domain, one PH domain and one SH3 domain. Defects in the gene encoding ARHGEF9 are a believed to be a cause for startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. This disease is a heterogenous neurological disorder characterized by muscular rigidity, particularly in the neonatal period, and a startle response to auditory or tactile stimuli.
Alternative Name:
Rho guanine nucleotide exchange factor 9, Collybistin, PEM-2 homolog, Rac/Cdc42 guanine nucleotide exchange factor 9, ARHGEF9, ARHDH9, KIAA0424
Application Dilution: WB: 1:500~1:1000
Specificity: ARHGEF9 polyclonal antibody detects endogenous levels of ARHGEF9 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ARHGEF9.
MW: ~ 54 kDa
Swis Prot.: O43307
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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