ARSE polyclonal, anti-human

ARSE polyclonal, anti-human

€305.00
In stock
SKU
BS5621
Catalog Number: BS5621
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, ICC

Datasheet
Background:
Arylsulfatase E, also known as CDPX, CDPX1 or CDPXR, is a 589 amino acid Golgi apparatus protein expressed in the pancreas, liver and kidney. Belonging to the sulfatase family, Arylsulfatase E may be essential for the correct composition of cartilage and bone matrix during development. Inhibited by warfarin, Arylsulfatase E activity occurs under optimal pH and temperature. Defects in the gene encoding Arylsulfatase E are the cause of chondrodysplasia punctata X-linked recessive type 1 (CDPX1), which is characterized by aberrant bone mineralization, severe underdevelopment of nasal cartilage and distal phalangeal hypoplasia. Arylsulfatase E has no activity toward steroid sulfates.

Alternative Name:
Arylsulfatase E, ASE, ARSE

Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200

Specificity: ARSE polyclonal antibody detects endogenous levels of ARSE protein.

Immunogen:
Synthetic peptide, corresponding to amino acids 208-253 of Human ARSE.

MW: ~ 66 kDa

Swis Prot.: P51690

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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