ATG4C polyclonal, anti-human, mouse, rat

Background:
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

Alternative Name:
APG4 autophagy 4 homolog C (S. cerevisiae), APG4 autophagy 4 homolog C, APG4 C, APG4C, ATG 4C, ATG4 autophagy related 4 homolog C (S. cerevisiae), Atg4c, ATG4C, AUT (S. cerevisiae) like 1, cysteine endopeptidase, AUT like 1, cysteine endopeptidase (S. cerevisiae), AUT like 1, cysteine endopeptidase, AUT like 3 cysteine endopeptidase, AUT-like 3 cysteine endopeptidase, AUTL1, AUTL3, Autophagin 3, Autophagin-3, Autophagy related cysteine endopeptidase 3, Autophagy related protein 4 homolog C

Application Dilution: WB: 1:500 - 1:2000

Specificity: ATG4C polyclonal antibody detects endogenous levels of ATG4C protein.

Immunogen:
Recombinant full length Human ATG4C.

MW: ~ 53 kDa

Swis Prot.: Q96DT6

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.