ATOX1 polyclonal, anti-human
€388.00
In stock
SKU
BS70749
Background:
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
Alternative Name:
ATX1, HAH1, Copper transport protein ATOX1
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: ATOX1 polyclonal antibody detects endogenous levels of ATOX1 protein.
Immunogen:
Recombinant protein of human ATOX1.
MW: ~ 7 kDa
Swis Prot.: O00244
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
Alternative Name:
ATX1, HAH1, Copper transport protein ATOX1
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: ATOX1 polyclonal antibody detects endogenous levels of ATOX1 protein.
Immunogen:
Recombinant protein of human ATOX1.
MW: ~ 7 kDa
Swis Prot.: O00244
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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