ATXN3 Antibody (Center) Blocking Peptide
€293.00
In stock
SKU
AC-BP9244c
Background:
ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.
Other Names: Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein, ATXN3, ATX3, MJD, MJD1, SCA3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9244c was selected from the Center region of human ATXN3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P54252
Gene ID: 4287
Gene Name: ATXN3
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Reina,C.P., et.al, Hum. Mol. Genet. 19 (2), 235-249 (2010)Jung,J., et.al, Hum. Mol. Genet. 18 (24), 4843-4852 (2009)
ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.
Other Names: Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein, ATXN3, ATX3, MJD, MJD1, SCA3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9244c was selected from the Center region of human ATXN3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P54252
Gene ID: 4287
Gene Name: ATXN3
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Reina,C.P., et.al, Hum. Mol. Genet. 19 (2), 235-249 (2010)Jung,J., et.al, Hum. Mol. Genet. 18 (24), 4843-4852 (2009)
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