B4GALT2 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61144
Background:
Several oligosaccharide structures and protein glycoconjugate types are found in nature. Homologous glycosyltransferase (GT) gene families catalyze the formation of glycosidic linkages. The beta-1,3 galactosyltransferase (β-1,3-Gal-T) gene family encodes a set of type II transmembrane glycoproteins that are catalytically diverse and use different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine) to catalyze the addition of an activated monosaccharide to a terminal lactose. The protein coding sequences for β-1,3-Gal-T genes comprise a single exon and are distantly related to the Drosophila Brainiac gene. The β-1,4-galactosyltransferase (-1,4-Gal-T) gene family encodes type II membrane-bound glycoproteins that show exclusive specificity for the donor substrate, UDP-galactose. β-1,4-Gal-T genes transfer galactose in a β-1,4 linkage to similar acceptor sugars; each gene has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. GTs on the surface of sperm in part mediate gamete adhesion by binding to appropriate carbohydrate substrates in the egg zona pellucida. In several tissues and cell lines, GTs localize to the Golgi complex.
Alternative Name:
Beta-1,4-galactosyltransferase 2 (EC:2.4.1.-), Beta-1,4-GalTase 2, Beta4Gal-T2, b4Gal-T2, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2, Lactose synthase A protein (EC:2.4.1.22), N-acetyllactosamine synthase (EC:2.4.1.90), Nal synthase, Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC:2.4.1.38), Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC:2.4.1.-), B4GALT2
Application Dilution: WB: 1:500~1:1000
Specificity: B4GALT2 polyclonal antibody detects endogenous levels of B4GALT2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human B4GALT2.
MW: ~ 44 kDa
Swis Prot.: O60909
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Several oligosaccharide structures and protein glycoconjugate types are found in nature. Homologous glycosyltransferase (GT) gene families catalyze the formation of glycosidic linkages. The beta-1,3 galactosyltransferase (β-1,3-Gal-T) gene family encodes a set of type II transmembrane glycoproteins that are catalytically diverse and use different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine) to catalyze the addition of an activated monosaccharide to a terminal lactose. The protein coding sequences for β-1,3-Gal-T genes comprise a single exon and are distantly related to the Drosophila Brainiac gene. The β-1,4-galactosyltransferase (-1,4-Gal-T) gene family encodes type II membrane-bound glycoproteins that show exclusive specificity for the donor substrate, UDP-galactose. β-1,4-Gal-T genes transfer galactose in a β-1,4 linkage to similar acceptor sugars; each gene has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. GTs on the surface of sperm in part mediate gamete adhesion by binding to appropriate carbohydrate substrates in the egg zona pellucida. In several tissues and cell lines, GTs localize to the Golgi complex.
Alternative Name:
Beta-1,4-galactosyltransferase 2 (EC:2.4.1.-), Beta-1,4-GalTase 2, Beta4Gal-T2, b4Gal-T2, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2, Lactose synthase A protein (EC:2.4.1.22), N-acetyllactosamine synthase (EC:2.4.1.90), Nal synthase, Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC:2.4.1.38), Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC:2.4.1.-), B4GALT2
Application Dilution: WB: 1:500~1:1000
Specificity: B4GALT2 polyclonal antibody detects endogenous levels of B4GALT2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human B4GALT2.
MW: ~ 44 kDa
Swis Prot.: O60909
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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