BAR2 Antibody (S261) Blocking Peptide
€293.00
In stock
SKU
AC-BP7263d
Background:
Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
Other Names: Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7263d was selected from the S261 region of human BAR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P07550
Other Accession: NP_000015
Gene ID: 154
Gene Name: ADRB2
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Wolfarth,B., Metab. Clin. Exp. 56 (12), 1649-1651 (2007)Cherezov,V., Science 318 (5854), 1258-1265 (2007)
Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
Other Names: Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7263d was selected from the S261 region of human BAR2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P07550
Other Accession: NP_000015
Gene ID: 154
Gene Name: ADRB2
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Wolfarth,B., Metab. Clin. Exp. 56 (12), 1649-1651 (2007)Cherezov,V., Science 318 (5854), 1258-1265 (2007)
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