BCAP29 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8141
Background:
BAP29 (BCR-associated protein 29), also known as BCAP29 (B-cell receptor-associated protein 29), is a multi-pass membrane protein localizing to the endoplasmic reticulum (ER) and belonging to the BCAP29/BCAP31 family of proteins. It is ubiquitously expressed with predominant expression in brain and testis. BAP29 contains a hydrophobic N-terminus, three transmembrane domains, a coiled-coil region and a C-terminal double-lysine motif that is implicated in vesicular transport. BAP29 exists as a homodimer or as a heterodimer with BAP31 and plays a role in membrane IgD molecule retention in the ER. In addition, the BAP29/BAP31 complex functions as a cargo receptor for MHC class I molecules and is important for recruiting the class I molecules to exit sites of the ER. The BAP29/BAP31 complex is also essential for proper trafficking from the ER to the Golgi.
Alternative Name:
B-cell receptor-associated protein 29, BCR-associated protein 29, Bap29, BCAP29, BAP29
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: BCAP29 polyclonal antibody detects endogenous levels of BCAP29 protein.
Immunogen:
Recombinant full length Human BCAP29.
MW: ~ 28 kDa
Swis Prot.: Q9UHQ4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
BAP29 (BCR-associated protein 29), also known as BCAP29 (B-cell receptor-associated protein 29), is a multi-pass membrane protein localizing to the endoplasmic reticulum (ER) and belonging to the BCAP29/BCAP31 family of proteins. It is ubiquitously expressed with predominant expression in brain and testis. BAP29 contains a hydrophobic N-terminus, three transmembrane domains, a coiled-coil region and a C-terminal double-lysine motif that is implicated in vesicular transport. BAP29 exists as a homodimer or as a heterodimer with BAP31 and plays a role in membrane IgD molecule retention in the ER. In addition, the BAP29/BAP31 complex functions as a cargo receptor for MHC class I molecules and is important for recruiting the class I molecules to exit sites of the ER. The BAP29/BAP31 complex is also essential for proper trafficking from the ER to the Golgi.
Alternative Name:
B-cell receptor-associated protein 29, BCR-associated protein 29, Bap29, BCAP29, BAP29
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: BCAP29 polyclonal antibody detects endogenous levels of BCAP29 protein.
Immunogen:
Recombinant full length Human BCAP29.
MW: ~ 28 kDa
Swis Prot.: Q9UHQ4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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