Bcl-7a (N62) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS9274
Background:
Bcl-7a (B-cell CLL/lymphoma 7 protein family member A) is a 210 amino acid protein that belongs to the Bcl-7 family. Chromosomal aberrations involving a disruption of the amino-terminus of Bcl-7a may be a cause of B-cell nonHodgkin lymphoma (BNHL). Bcl-7b and Bcl-7c proteins share 90% identity with the N-terminal 51 amino acids of Bcl-7a, suggesting that the three genes are members of an evolutionarily conserved gene family. Bcl-7 gene family may be involved in early development. The Bcl-7a protein interacts with a novel human Polycomb ring finger gene and exists as two alternatively spliced isoforms. Bcl-7a may play a role in GC reaction and/or B-cell lymphomagenesis. The Bcl-7a gene maps to human chromosome 12q24.31. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Alternative Name:
B cell CLL/lymphoma 7, B cell CLL/lymphoma 7 protein family member A, B cell CLL/lymphoma 7A, B-cell CLL/lymphoma 7 protein family member A, BCL 7, BCL7, bcl7a, BCL7A
Application Dilution: WB: 1:500~1:1000
Specificity: Bcl-7a (N62) polyclonal antibody detects endogenous levels of Bcl-7a protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 30-84 of Human Bcl-7a.
MW: ~ 23 kDa
Swis Prot.: Q4VC05
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Bcl-7a (B-cell CLL/lymphoma 7 protein family member A) is a 210 amino acid protein that belongs to the Bcl-7 family. Chromosomal aberrations involving a disruption of the amino-terminus of Bcl-7a may be a cause of B-cell nonHodgkin lymphoma (BNHL). Bcl-7b and Bcl-7c proteins share 90% identity with the N-terminal 51 amino acids of Bcl-7a, suggesting that the three genes are members of an evolutionarily conserved gene family. Bcl-7 gene family may be involved in early development. The Bcl-7a protein interacts with a novel human Polycomb ring finger gene and exists as two alternatively spliced isoforms. Bcl-7a may play a role in GC reaction and/or B-cell lymphomagenesis. The Bcl-7a gene maps to human chromosome 12q24.31. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Alternative Name:
B cell CLL/lymphoma 7, B cell CLL/lymphoma 7 protein family member A, B cell CLL/lymphoma 7A, B-cell CLL/lymphoma 7 protein family member A, BCL 7, BCL7, bcl7a, BCL7A
Application Dilution: WB: 1:500~1:1000
Specificity: Bcl-7a (N62) polyclonal antibody detects endogenous levels of Bcl-7a protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 30-84 of Human Bcl-7a.
MW: ~ 23 kDa
Swis Prot.: Q4VC05
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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