BCL2L14 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8249
Background:
Apoptosis is defined as a set of cascades which, when initiated, program the cell to undergo lethal changes such as membrane blebbing, mitochondrial breakdown and DNA fragmentation. Bcl-2 is one of many key regulators of apoptosis that are essential for proper development, tissue homeostasis and protection against foreign pathogens. Bcl-G, also known as BCL2L14 (BCL2-like 14) or BCLG, is a 327 amino acid cytoplasmic protein that belongs to the Bcl-2 family of apoptosis-regulating proteins. Bcl-G is expressed as three alternatively spliced transcripts designated short, medium and long. The short isoform is testis-specific and localizes to cytosolic organelles, while the long isoform is widely expressed and is distributed throughout the cytosol. Overexpression of Bcl-G induces apoptosis in cells, suggesting a possible role for Bcl-G in tumor suppression.
Alternative Name:
Apoptosis facilitator Bcl-2-like protein 14, Bcl2-L-14, Apoptosis regulator Bcl-G, BCL2L14, BCLG
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: BCL2L14 polyclonal antibody detects endogenous levels of BCL2L14 protein.
Immunogen:
Recombinant full length Human BCL2L14.
MW: ~ 37 kDa
Swis Prot.: Q9BZR8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Apoptosis is defined as a set of cascades which, when initiated, program the cell to undergo lethal changes such as membrane blebbing, mitochondrial breakdown and DNA fragmentation. Bcl-2 is one of many key regulators of apoptosis that are essential for proper development, tissue homeostasis and protection against foreign pathogens. Bcl-G, also known as BCL2L14 (BCL2-like 14) or BCLG, is a 327 amino acid cytoplasmic protein that belongs to the Bcl-2 family of apoptosis-regulating proteins. Bcl-G is expressed as three alternatively spliced transcripts designated short, medium and long. The short isoform is testis-specific and localizes to cytosolic organelles, while the long isoform is widely expressed and is distributed throughout the cytosol. Overexpression of Bcl-G induces apoptosis in cells, suggesting a possible role for Bcl-G in tumor suppression.
Alternative Name:
Apoptosis facilitator Bcl-2-like protein 14, Bcl2-L-14, Apoptosis regulator Bcl-G, BCL2L14, BCLG
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: BCL2L14 polyclonal antibody detects endogenous levels of BCL2L14 protein.
Immunogen:
Recombinant full length Human BCL2L14.
MW: ~ 37 kDa
Swis Prot.: Q9BZR8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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