BLMH polyclonal, anti-human, rat
€388.00
In stock
SKU
BS6469
Background:
BLM hydrolase (Bleomycin hydrolase, BLM hydrolase, BMH) is a 455 amino acid protein encoded by the human gene BLMH. BLM hydrolase belongs to the cysteine protease papain superfamily and the peptidase C1 family. It is a cytoplasmic cysteine peptidase commonly found as a homohexamer. It is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM). BLM is an essential component of combination chemotherapy regimens for cancer.
Alternative Name:
Bleomycin hydrolase, BH, BLM hydrolase, BMH, BLMH
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: BLMH polyclonal antibody detects endogenous levels of BLMH protein.
Immunogen:
Recombinant full length Human BLMH.
MW: ~ 53 kDa
Swis Prot.: Q13867
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
BLM hydrolase (Bleomycin hydrolase, BLM hydrolase, BMH) is a 455 amino acid protein encoded by the human gene BLMH. BLM hydrolase belongs to the cysteine protease papain superfamily and the peptidase C1 family. It is a cytoplasmic cysteine peptidase commonly found as a homohexamer. It is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM). BLM is an essential component of combination chemotherapy regimens for cancer.
Alternative Name:
Bleomycin hydrolase, BH, BLM hydrolase, BMH, BLMH
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: BLMH polyclonal antibody detects endogenous levels of BLMH protein.
Immunogen:
Recombinant full length Human BLMH.
MW: ~ 53 kDa
Swis Prot.: Q13867
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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