BRD2 polyclonal, anti-human

Background:
The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.

Alternative Name:
Bromodomain-containing protein 2, O27.1.1, Really interesting new gene 3 protein, BRD2, KIAA9001, RING3

Application Dilution: WB: 1:500-1:2000, IHC: 1:50-1:200, ICC: 1:50-1:200, FC: 1:50-1:100

Specificity: This antibody detects endogenous levels of BRD2 and does not cross-react with related proteins.

Immunogen:
Recombinant protein within human BRD2 aa 1-200.

MW: ~ 88 kDa

Swis Prot.: P25440

Purification & Purity:
Protein A affinity purified.

Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.