BTRC polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6777
Background:
ß-TrCP (beta-tranducin repeats containing protein), also designated E3RSIkB or FWD1, and HOS (homologous to Slimb) are F-box proteins that function as substrate recognition subunits of ubiquitin ligases. HOS and ß-TrCP differ in their amino terminal regions, but exhibit high homology within the F-box and WD40 repeat-containing regions. ß-TrCP mediates ubiquitin/proteasome-dependent degradation of CD4 and ubiquitination of various proteins including IkB and ß-catenin. HOS has also been shown to regulate the degradation of IkB and ß-catenin in a similar manner.
Alternative Name:
Beta transducin repeat containing E3 ubiquitin protein ligase, beta TrCP1, beta-transducin repeat containing, BETA-TRCP, betaTrCP, BTRC, bTrCP, bTrCP1, E3RSIkappaB, F box and WD repeat protein 1B, F box and WD repeats protein beta TrCP, F-box and WD repeats protein beta-TrCP, F-box/WD repeat protein 1A, F-box/WD repeat-containing protein 1A, FBW1A, FBW1A, FBXW1, FBXW1A, FWD1, HOS, mKIAA4123, pIkappaBalpha-E3 receptor subunit, Slimb,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: BTRC polyclonal antibody detects endogenous levels of BTRC protein.
Immunogen:
Recombinant full length Human BTRC.
MW: ~ 68 kDa
Swis Prot.: Q9Y297
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
ß-TrCP (beta-tranducin repeats containing protein), also designated E3RSIkB or FWD1, and HOS (homologous to Slimb) are F-box proteins that function as substrate recognition subunits of ubiquitin ligases. HOS and ß-TrCP differ in their amino terminal regions, but exhibit high homology within the F-box and WD40 repeat-containing regions. ß-TrCP mediates ubiquitin/proteasome-dependent degradation of CD4 and ubiquitination of various proteins including IkB and ß-catenin. HOS has also been shown to regulate the degradation of IkB and ß-catenin in a similar manner.
Alternative Name:
Beta transducin repeat containing E3 ubiquitin protein ligase, beta TrCP1, beta-transducin repeat containing, BETA-TRCP, betaTrCP, BTRC, bTrCP, bTrCP1, E3RSIkappaB, F box and WD repeat protein 1B, F box and WD repeats protein beta TrCP, F-box and WD repeats protein beta-TrCP, F-box/WD repeat protein 1A, F-box/WD repeat-containing protein 1A, FBW1A, FBW1A, FBXW1, FBXW1A, FWD1, HOS, mKIAA4123, pIkappaBalpha-E3 receptor subunit, Slimb,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100
Specificity: BTRC polyclonal antibody detects endogenous levels of BTRC protein.
Immunogen:
Recombinant full length Human BTRC.
MW: ~ 68 kDa
Swis Prot.: Q9Y297
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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