BVES polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6011
Background:
Blood vessel epicardial substance (BVES), also designated Popeye protein 1, is a transmembrane protein that plays a role in cell-cell interactions and adhesion, specifically at tight junctions. BVES is composed of an extracellular amino-terminus, three transmembrane domains and a cytoplasmic carboxyl-terminus. It is expressed in the developing coronary vascular system, specifically in the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells, where it functions to direct development in heart, epithelial and muscle cells during embryogenesis. BVES accumulates at points of cell-cell contact, such as filopodia and cell borders, and promotes adhesion prior to the arrival of E-cadherin.
Alternative Name:
Blood vessel epicardial substance, HBVES, MGC42413, POP 1, POP1, POPDC 1, POPDC1, Popeye domain containing 1, Popeye domain containing protein 1, Popeye protein 1,
Application Dilution: WB: 1:500~1:2000
Specificity: BVES polyclonal antibody detects endogenous levels of BVES protein.
Immunogen:
Recombinant full length Human BVES.
MW: ~ 41 kDa
Swis Prot.: Q8NE79
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Blood vessel epicardial substance (BVES), also designated Popeye protein 1, is a transmembrane protein that plays a role in cell-cell interactions and adhesion, specifically at tight junctions. BVES is composed of an extracellular amino-terminus, three transmembrane domains and a cytoplasmic carboxyl-terminus. It is expressed in the developing coronary vascular system, specifically in the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells, where it functions to direct development in heart, epithelial and muscle cells during embryogenesis. BVES accumulates at points of cell-cell contact, such as filopodia and cell borders, and promotes adhesion prior to the arrival of E-cadherin.
Alternative Name:
Blood vessel epicardial substance, HBVES, MGC42413, POP 1, POP1, POPDC 1, POPDC1, Popeye domain containing 1, Popeye domain containing protein 1, Popeye protein 1,
Application Dilution: WB: 1:500~1:2000
Specificity: BVES polyclonal antibody detects endogenous levels of BVES protein.
Immunogen:
Recombinant full length Human BVES.
MW: ~ 41 kDa
Swis Prot.: Q8NE79
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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