c-Myb (I526) polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS3769
Background:
c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc. c-Myb is expressed predominantly in immature and rapidly dividing hematopoietic cells, and cellular levels of c-Myb substantially decreases as cells reach terminal differentiation. B-Myb is expressed in a wide variety of proliferating cells, with levels accumulating during the G1 to S phase transition. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes.
Alternative Name:
Transcriptional activator Myb, Proto-oncogene c-Myb, MYB
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: c-Myb (I526) polyclonal antibody detects endogenous levels of c-Myb protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 491-540 of Human c-Myb.
MW: ~ 80 kDa
Swis Prot.: P10242
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc. c-Myb is expressed predominantly in immature and rapidly dividing hematopoietic cells, and cellular levels of c-Myb substantially decreases as cells reach terminal differentiation. B-Myb is expressed in a wide variety of proliferating cells, with levels accumulating during the G1 to S phase transition. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes.
Alternative Name:
Transcriptional activator Myb, Proto-oncogene c-Myb, MYB
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: c-Myb (I526) polyclonal antibody detects endogenous levels of c-Myb protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 491-540 of Human c-Myb.
MW: ~ 80 kDa
Swis Prot.: P10242
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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