c-Src (S69) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3754
Background:
The major translational products of each of the eight members of the Src gene family identified to date are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences, thereby distinguishing this group from the receptor class of tyrosine kinases. Members of this group include c-Src, c-Yes, Fyn, Lck, Lyn, Blk and c-Fgr. The major Src gene encoded protein, c-Src (also designated pp60Src, Src p60 and proto-oncogene tyrosine protein kinase Src) is expressed in a broad range of tissue and cell types, although the highest levels of c-Src are detected in neuronal tissues and platelets. c-Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.
Alternative Name:
Proto-oncogene tyrosine-protein kinase Src, 2.7.10.2, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC1, SRC
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: c-Src (S69) polyclonal antibody detects endogenous levels of c-Src protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 40-80 of Human c-Src.
MW: ~ 60 kDa
Swis Prot.: P12931
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The major translational products of each of the eight members of the Src gene family identified to date are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences, thereby distinguishing this group from the receptor class of tyrosine kinases. Members of this group include c-Src, c-Yes, Fyn, Lck, Lyn, Blk and c-Fgr. The major Src gene encoded protein, c-Src (also designated pp60Src, Src p60 and proto-oncogene tyrosine protein kinase Src) is expressed in a broad range of tissue and cell types, although the highest levels of c-Src are detected in neuronal tissues and platelets. c-Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.
Alternative Name:
Proto-oncogene tyrosine-protein kinase Src, 2.7.10.2, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC1, SRC
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: c-Src (S69) polyclonal antibody detects endogenous levels of c-Src protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 40-80 of Human c-Src.
MW: ~ 60 kDa
Swis Prot.: P12931
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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