C1D polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8224
Background:
C1D, also known as SUNCOR, is a nuclear DNA-binding protein that localizes to the nucleus and cytoplasm and participates in processing of the 5.8S rRNA. Expressed ubiquitously with highest expression in thyroid, salivary gland, hippocampus and medulla oblongata, C1D forms a multi-protein complex with MPP6 (M phase phosphoprotein 6) and EXOSC10 (exosome component 10). This complex is responsible, in part, for recruiting the exosome to pre-rRNA and it functions to mediate 3’-5’ rRNA processing. Additionally, C1D can induce transcriptional repression and apoptosis through interaction with Rev-erbα (V-erbA-related protein EAR-1)/TRβ (thyroid hormone receptor β) and p53, respectively. C1D, a 141 amino acid protein, is also implicated in DNA repair mechanisms, as well as DNA-PK (DNA-dependent protein kinase) activation.
Alternative Name:
1110036E10Rik, AI875855, C1D, C1D DNA binding protein, C1D_HUMAN, hC1D, LRP1, MGC12261, MGC14659, MGC188504, Nuclear DNA binding protein, Nuclear nucleic acid binding protein C1D, Nuclear nucleic acid-binding protein C1D, rCG23324, RGD1560600, Small unique nuclear receptor corepressor, SUNCOR
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: C1D polyclonal antibody detects endogenous levels of C1D protein.
Immunogen:
Recombinant full length Human C1D.
MW: ~ 16 kDa
Swis Prot.: Q13901
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
C1D, also known as SUNCOR, is a nuclear DNA-binding protein that localizes to the nucleus and cytoplasm and participates in processing of the 5.8S rRNA. Expressed ubiquitously with highest expression in thyroid, salivary gland, hippocampus and medulla oblongata, C1D forms a multi-protein complex with MPP6 (M phase phosphoprotein 6) and EXOSC10 (exosome component 10). This complex is responsible, in part, for recruiting the exosome to pre-rRNA and it functions to mediate 3’-5’ rRNA processing. Additionally, C1D can induce transcriptional repression and apoptosis through interaction with Rev-erbα (V-erbA-related protein EAR-1)/TRβ (thyroid hormone receptor β) and p53, respectively. C1D, a 141 amino acid protein, is also implicated in DNA repair mechanisms, as well as DNA-PK (DNA-dependent protein kinase) activation.
Alternative Name:
1110036E10Rik, AI875855, C1D, C1D DNA binding protein, C1D_HUMAN, hC1D, LRP1, MGC12261, MGC14659, MGC188504, Nuclear DNA binding protein, Nuclear nucleic acid binding protein C1D, Nuclear nucleic acid-binding protein C1D, rCG23324, RGD1560600, Small unique nuclear receptor corepressor, SUNCOR
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: C1D polyclonal antibody detects endogenous levels of C1D protein.
Immunogen:
Recombinant full length Human C1D.
MW: ~ 16 kDa
Swis Prot.: Q13901
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review