C7 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7763
Background:
Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Involvement in disease: Defects in C7 are a cause of complement component 7 deficiency (C7D) [MIM:610102]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
Alternative Name:
C7, CO7_HUMAN, complement component 7, Complement component C7,
Application Dilution: WB: 1:500 - 1:2000
Specificity: C7 polyclonal antibody detects endogenous levels of C7 protein.
Immunogen:
Recombinant full length Human C7.
MW: ~ 94 kDa
Swis Prot.: P10643
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Involvement in disease: Defects in C7 are a cause of complement component 7 deficiency (C7D) [MIM:610102]. A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis.
Alternative Name:
C7, CO7_HUMAN, complement component 7, Complement component C7,
Application Dilution: WB: 1:500 - 1:2000
Specificity: C7 polyclonal antibody detects endogenous levels of C7 protein.
Immunogen:
Recombinant full length Human C7.
MW: ~ 94 kDa
Swis Prot.: P10643
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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