CA13 polyclonal, anti-human
€305.00
In stock
SKU
BS61599
Background:
Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XIII, also referred to as carbonate dehydratase XIII, is predominantly expressed in spleen, prostate, thymus, ovary, testis, colon and small intestine localizing to the cytoplasm. It exhibits highest homology with family members CA I, CA II and CA III. CA XIII may play a role in embryogenesis. Efficient inhibitors of CA XIII activity are sulfanilyl-sulfonamide type inhibitors.
Alternative Name:
Carbonic anhydrase 13, Carbonate dehydratase XIII, Carbonic anhydrase XIII, CA-XIII
Application Dilution: WB: 1:500~1:1000
Specificity: CA13 polyclonal antibody detects endogenous levels of CA13 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 142-186 of Human CA13.
MW: ~ 36 kDa
Swis Prot.: Q8N1Q1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 104% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA XIII, also referred to as carbonate dehydratase XIII, is predominantly expressed in spleen, prostate, thymus, ovary, testis, colon and small intestine localizing to the cytoplasm. It exhibits highest homology with family members CA I, CA II and CA III. CA XIII may play a role in embryogenesis. Efficient inhibitors of CA XIII activity are sulfanilyl-sulfonamide type inhibitors.
Alternative Name:
Carbonic anhydrase 13, Carbonate dehydratase XIII, Carbonic anhydrase XIII, CA-XIII
Application Dilution: WB: 1:500~1:1000
Specificity: CA13 polyclonal antibody detects endogenous levels of CA13 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 142-186 of Human CA13.
MW: ~ 36 kDa
Swis Prot.: Q8N1Q1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 104% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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