CA8 polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS61149
Background:
Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA VIII, also referred to as carbonic anhydrase-related protein VIII (CA-RP VIII), is a member of the carbonic anhydrase family that lacks the Zn-binding motif essential for carbonic anhydrase activity. For this reason, CA VIII does not exhibit catalytic activity but instead may be important in synaptic vesicle formation and transport. In addition, CA VIII may be involved in the invasiveness of non-small cell lung carcinomas and may also play a role in the growth of colon cancer cells.
Alternative Name:
Carbonic anhydrase-related protein, CARP, Carbonic anhydrase VIII, CA-VIII, CA8, CALS
Application Dilution: WB: 1:500~1:1000
Specificity: CA8 polyclonal antibody detects endogenous levels of CA8 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CA8.
MW: ~ 35 kDa
Swis Prot.: P35219
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA VIII, also referred to as carbonic anhydrase-related protein VIII (CA-RP VIII), is a member of the carbonic anhydrase family that lacks the Zn-binding motif essential for carbonic anhydrase activity. For this reason, CA VIII does not exhibit catalytic activity but instead may be important in synaptic vesicle formation and transport. In addition, CA VIII may be involved in the invasiveness of non-small cell lung carcinomas and may also play a role in the growth of colon cancer cells.
Alternative Name:
Carbonic anhydrase-related protein, CARP, Carbonic anhydrase VIII, CA-VIII, CA8, CALS
Application Dilution: WB: 1:500~1:1000
Specificity: CA8 polyclonal antibody detects endogenous levels of CA8 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CA8.
MW: ~ 35 kDa
Swis Prot.: P35219
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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