CaMKV (N217) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS2493
Catalog Number: BS2493
Size: 100 µl
Other Size: 50 µl
Isotype: rabbit IgG
Applications: WB
Questions? Contact us!
Size: 100 µl
Other Size: 50 µl
Isotype: rabbit IgG
Applications: WB
Questions? Contact us!
Background:
The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CAMKV (CaM kinaselike vesicle-associated), also known as 1G5 or VACAMKL, is a 501 amino acid protein that localizes to cytoplasmic vesicles, as well as to the cell membrane, and contains one protein kinase domain. Although a member of the CaMK family, CaMKV is thought to be catalytically inactive, but it may play a role in vesicle function and nervous system development. Multiple isoforms of CaMKV exist due to alternative splicing events. The gene encoding CaMKV maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and CharcotMarie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Alternative Name:
CaM kinase-like vesicle-associated protein, CAMKV
Application Dilution:
WB: 1:1000~1:2000
Specificity: CaMKV (N217) polyclonal antibody detects endogenous levels of CaMKV protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 186-247 of Human CaMKV.
MW: ~ 54 kDa
Swiss-Prot: Q8NCB2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Ca2+/calmodulin-dependent protein kinases (CaMKs) comprise a structurally related subfamily of serine/threonine kinases. CAMKV (CaM kinaselike vesicle-associated), also known as 1G5 or VACAMKL, is a 501 amino acid protein that localizes to cytoplasmic vesicles, as well as to the cell membrane, and contains one protein kinase domain. Although a member of the CaMK family, CaMKV is thought to be catalytically inactive, but it may play a role in vesicle function and nervous system development. Multiple isoforms of CaMKV exist due to alternative splicing events. The gene encoding CaMKV maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and CharcotMarie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Alternative Name:
CaM kinase-like vesicle-associated protein, CAMKV
Application Dilution:
WB: 1:1000~1:2000
Specificity: CaMKV (N217) polyclonal antibody detects endogenous levels of CaMKV protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 186-247 of Human CaMKV.
MW: ~ 54 kDa
Swiss-Prot: Q8NCB2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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