CARD8 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6022
Background:
The MAGUK family includes several mammalian proteins, such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1-3), and the caspase-associated recruitment domain (CARD) proteins, all of which are related to the Drosophila tumor suppressor discs-large (dlg) gene product. CARD 8, also designated DACAR, NDPP1, TUCAN or CARDINAL, is a 431 amino acid protein that is expressed in the lung, ovary, testis, and placenta. It regulates cellular responses controlled by NF-˚ B activation and may play a key role in apoptosis and chronic inflammatory disorders. CARD 8 binds to caspase-1 and negatively regulates its activity.
Alternative Name:
Apoptotic protein NDPP 1, Apoptotic protein NDPP1, CARD 8, CARD inhibitor of NF kappa B activating ligand, CARD inhibitor of NF kappaB activating ligand, CARD inhibitor of NF kappaB activating ligands, CARD-inhibitor of NF-kappa-B-activating ligand, CARD8, CARD8, CARDINAL, Caspase recruitment domain containing protein 8, Caspase recruitment domain family member 8, Caspase recruitment domain protein 8, Caspase recruitment domain-containing protein 8, DACAR, DKFZp779L0366, KI
Application Dilution: WB: 1:500 - 1:2000
Specificity: CARD8 polyclonal antibody detects endogenous levels of CARD8 protein.
Immunogen:
Recombinant full length Human CARD8.
MW: ~ 49 kDa
Swis Prot.: Q9Y2G2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The MAGUK family includes several mammalian proteins, such as postsynaptic proteins, GKAPs, the tight junction associated proteins (ZO-1-3), and the caspase-associated recruitment domain (CARD) proteins, all of which are related to the Drosophila tumor suppressor discs-large (dlg) gene product. CARD 8, also designated DACAR, NDPP1, TUCAN or CARDINAL, is a 431 amino acid protein that is expressed in the lung, ovary, testis, and placenta. It regulates cellular responses controlled by NF-˚ B activation and may play a key role in apoptosis and chronic inflammatory disorders. CARD 8 binds to caspase-1 and negatively regulates its activity.
Alternative Name:
Apoptotic protein NDPP 1, Apoptotic protein NDPP1, CARD 8, CARD inhibitor of NF kappa B activating ligand, CARD inhibitor of NF kappaB activating ligand, CARD inhibitor of NF kappaB activating ligands, CARD-inhibitor of NF-kappa-B-activating ligand, CARD8, CARD8, CARDINAL, Caspase recruitment domain containing protein 8, Caspase recruitment domain family member 8, Caspase recruitment domain protein 8, Caspase recruitment domain-containing protein 8, DACAR, DKFZp779L0366, KI
Application Dilution: WB: 1:500 - 1:2000
Specificity: CARD8 polyclonal antibody detects endogenous levels of CARD8 protein.
Immunogen:
Recombinant full length Human CARD8.
MW: ~ 49 kDa
Swis Prot.: Q9Y2G2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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