Casein Kinase Iγ3 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60318
Background:
Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, ε and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an ααβ2' structure. The α catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Alternative Name:
Casein kinase I isoform gamma-3, CKI-gamma 3, CSNK1G3, CKIγ3, CK-Iγ3
Application Dilution: WB: 1:500~1:1000
Specificity: Casein Kinase Iγ3 polyclonal antibody detects endogenous levels of Casein Kinase Iγ3 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Casein Kinase Iγ3.
MW: ~ 55 kDa
Swis Prot.: Q9Y6M4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, ε and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an ααβ2' structure. The α catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Alternative Name:
Casein kinase I isoform gamma-3, CKI-gamma 3, CSNK1G3, CKIγ3, CK-Iγ3
Application Dilution: WB: 1:500~1:1000
Specificity: Casein Kinase Iγ3 polyclonal antibody detects endogenous levels of Casein Kinase Iγ3 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Casein Kinase Iγ3.
MW: ~ 55 kDa
Swis Prot.: Q9Y6M4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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