CASP8AP2 polyclonal, anti-human
€388.00
In stock
SKU
BS72749
Background:
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Alternative Name:
CED-4,FLASH,RIP25
Application Dilution: WB: 1:500 - 1:2000
Specificity: CASP8AP2 polyclonal antibody detects endogenous levels of CASP8AP2 protein.
Immunogen:
Recombinant protein of human CASP8AP2
MW: 215kDa
Swis Prot.: Q9UKL3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Alternative Name:
CED-4,FLASH,RIP25
Application Dilution: WB: 1:500 - 1:2000
Specificity: CASP8AP2 polyclonal antibody detects endogenous levels of CASP8AP2 protein.
Immunogen:
Recombinant protein of human CASP8AP2
MW: 215kDa
Swis Prot.: Q9UKL3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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