Catenin-δ1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6572
Background:
The α, β, δ, and γ -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. δ-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding δ-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding δ-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. γ-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds α-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling.
Alternative Name:
Catenin δ1, Catenin delta-1, Cadherin-associated Src substrate, Short name=CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: Catenin-δ1 polyclonal antibody detects endogenous levels of Catenin-δ1 protein.
Immunogen:
Recombinant full length Human Catenin-δ1.
MW: ~ 108 kDa
Swis Prot.: O60716
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The α, β, δ, and γ -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. δ-catenin interacts with Presenilin 1 and is expressed in the brain. The gene encoding δ-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding δ-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. γ-catenin, also known as plakoglobin, is an 80-88 kDa protein that binds α-catenin and N-cadherin. In addition, the transmembrane phosphatase PTPm associates with catenin/cadherin complexes and may regulate complex signaling.
Alternative Name:
Catenin δ1, Catenin delta-1, Cadherin-associated Src substrate, Short name=CAS, p120 catenin, p120(ctn), p120(cas), CTNND1, KIAA0384
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: Catenin-δ1 polyclonal antibody detects endogenous levels of Catenin-δ1 protein.
Immunogen:
Recombinant full length Human Catenin-δ1.
MW: ~ 108 kDa
Swis Prot.: O60716
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review