Cathepsin D (HC) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS7022
Background:
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.
Alternative Name:
Cathepsin D, Cathepsin D heavy chain, CTSD, CPSD
Application Dilution: WB: 1:500~1:1000
Specificity: Cathepsin D (HC) polyclonal antibody detects endogenous levels of Cathepsin D heavy chain (27 kDa) Protein.
Immunogen:
Recombinant full length Human Cathepsin D (Heavy chain).
MW: ~ 27, 43, 45 kDa
Swis Prot.: P07339
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.
Alternative Name:
Cathepsin D, Cathepsin D heavy chain, CTSD, CPSD
Application Dilution: WB: 1:500~1:1000
Specificity: Cathepsin D (HC) polyclonal antibody detects endogenous levels of Cathepsin D heavy chain (27 kDa) Protein.
Immunogen:
Recombinant full length Human Cathepsin D (Heavy chain).
MW: ~ 27, 43, 45 kDa
Swis Prot.: P07339
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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