CHIT1 (clone 1D9G2,1D9G4,2B4G3), anti-human
€394.00
In stock
SKU
252851
Catalog Nr.: 252851
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Protein Family: Enzymes
Pathway and Disease: Carbohydrate Metabolism
Description:
CHIT1 (Chitinase 1) is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Alternate Names: Chitotriosidase, CHI3, CHIT, FLJ00314, MGC125322, CHIT1
Application Notes: WB: 1:500-1:2000
Accession No.: Q13231
Antigen: Purified recombinant fragment of CHIT1(aa22-137) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Carbohydrate Metabolism
Description:
CHIT1 (Chitinase 1) is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Alternate Names: Chitotriosidase, CHI3, CHIT, FLJ00314, MGC125322, CHIT1
Application Notes: WB: 1:500-1:2000
Accession No.: Q13231
Antigen: Purified recombinant fragment of CHIT1(aa22-137) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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