COBRA1 (clone ), anti-human, mouse, rat, rabbit, sheep
€418.00
In stock
SKU
253121
Catalog Nr.: 253121
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB
Protein Family: Transcription Factors
Pathway and Disease: Transcription
Description:
Cofactor of BRCA1 (negative elongation factor B, NELF-B, COBRA1) is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. COBRA1 can induce chromatin unfolding.
Alternate Names: Negative elongation factor B, NELF-B, Cofactor of BRCA1, COBRA1, KIAA1182, NELFB
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: Q8WX92
Antigen: Recombinant full length human COBRA1 expressed in E. coli.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Transcription
Description:
Cofactor of BRCA1 (negative elongation factor B, NELF-B, COBRA1) is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. COBRA1 can induce chromatin unfolding.
Alternate Names: Negative elongation factor B, NELF-B, Cofactor of BRCA1, COBRA1, KIAA1182, NELFB
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: Q8WX92
Antigen: Recombinant full length human COBRA1 expressed in E. coli.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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