HNRNPM Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14009a
Background:
This gene belongs to the subfamily of ubiquitouslyexpressed heterogeneous nuclear ribonucleoproteins (hnRNPs). ThehnRNPs are RNA binding proteins and they complex with heterogeneousnuclear RNA (hnRNA). These proteins are associated with pre-mRNAsin the nucleus and appear to influence pre-mRNA processing andother aspects of mRNA metabolism and transport. While all of thehnRNPs are present in the nucleus, some seem to shuttle between thenucleus and the cytoplasm. The hnRNP proteins have distinct nucleicacid binding properties. The protein encoded by this gene has threerepeats of quasi-RRM domains that bind to RNAs. This protein alsoconstitutes a monomer of the N-acetylglucosamine-specific receptorwhich is postulated to trigger selective recycling of immatureGlcNAc-bearing thyroglobulin molecules. Multiple alternativelyspliced transcript variants are known for this gene but only twotranscripts has been isolated.
Other Names:
Heterogeneous nuclear ribonucleoprotein M, hnRNP M, HNRNPM, HNRPM, NAGR1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14009a was selected from the N-term region of HNRNPM. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HNRNPM
Gene ID: 4670
Primary Accession: P52272
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene belongs to the subfamily of ubiquitouslyexpressed heterogeneous nuclear ribonucleoproteins (hnRNPs). ThehnRNPs are RNA binding proteins and they complex with heterogeneousnuclear RNA (hnRNA). These proteins are associated with pre-mRNAsin the nucleus and appear to influence pre-mRNA processing andother aspects of mRNA metabolism and transport. While all of thehnRNPs are present in the nucleus, some seem to shuttle between thenucleus and the cytoplasm. The hnRNP proteins have distinct nucleicacid binding properties. The protein encoded by this gene has threerepeats of quasi-RRM domains that bind to RNAs. This protein alsoconstitutes a monomer of the N-acetylglucosamine-specific receptorwhich is postulated to trigger selective recycling of immatureGlcNAc-bearing thyroglobulin molecules. Multiple alternativelyspliced transcript variants are known for this gene but only twotranscripts has been isolated.
Other Names:
Heterogeneous nuclear ribonucleoprotein M, hnRNP M, HNRNPM, HNRPM, NAGR1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14009a was selected from the N-term region of HNRNPM. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HNRNPM
Gene ID: 4670
Primary Accession: P52272
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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