I-TAC human active recombinant protein
€295.00
In stock
SKU
600314
Protein Family: Cellular Antigens, Cytokines
Pathway and Disease: Cell Growth and Death, Immune System, Signaling Molecules and Interaction
Alternate Names: CXCL11, B-R1Description:
Interferon Inducible T cell Alpha Chemokine (I-TAC), or CXCL11, expressed at high levels in leukocytes, pancreas and liver exposed to IFNalpha, beta, and gamma. I-TAC is one of three chemokines known to bind the receptor CXCR3 (the two others being CXCL9 and CXCL10 (IP-10)) to act as a chemoattractant for IL-2 activated T cells. CXCL11 differs from the other CXCR3 ligands in that it has a higher receptor affinity, thus acts as a stronger agonist. Human I-TAC is produced in E.coli. Recombinant human I-TAC is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 8.3 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The biological activity can be determined by the ability to chemoattract IL-2 activated T cells at a concentration of 0.1-10 ng/mL. There is no biological assay data available at this time. Specific activity: 1 x 10e7 units/mg
Accession No.: O14625
MW: 8307 Da
Sequence:
FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Cell Growth and Death, Immune System, Signaling Molecules and Interaction
Alternate Names: CXCL11, B-R1Description:
Interferon Inducible T cell Alpha Chemokine (I-TAC), or CXCL11, expressed at high levels in leukocytes, pancreas and liver exposed to IFNalpha, beta, and gamma. I-TAC is one of three chemokines known to bind the receptor CXCR3 (the two others being CXCL9 and CXCL10 (IP-10)) to act as a chemoattractant for IL-2 activated T cells. CXCL11 differs from the other CXCR3 ligands in that it has a higher receptor affinity, thus acts as a stronger agonist. Human I-TAC is produced in E.coli. Recombinant human I-TAC is a non-glycosylated protein, containing 73 amino acids, with a molecular weight of 8.3 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The biological activity can be determined by the ability to chemoattract IL-2 activated T cells at a concentration of 0.1-10 ng/mL. There is no biological assay data available at this time. Specific activity: 1 x 10e7 units/mg
Accession No.: O14625
MW: 8307 Da
Sequence:
FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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