IGF-2 human active recombinant protein

IGF-2 human active recombinant protein

€295.00
In stock
SKU
600125
Catalog Number: 600125
Size: 0.05 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Cancers, Cell Growth and Death, Cell Communication, Nervous and Sensory Systems, Signal Transduction

Alternate Names: Insulin-like growth factor II, IGF-II, somatomedin-A, insulin-like growth factor II Ala-25 Del, Preptin, IGF2Description:
Insulin-like growth factor II (IGF2) has growth-promoting activities and is a potent mitogen for cultured cells. IGF2 is a major fetal growth factor with role in fetal development. Recombinant Human IGF2 produced in E. coli is a single non-glycosylated polypeptide chain containing 67 amino acids with a MW of 7,505 Da.

Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.

Applications: E, WB

Application Notes:
Recombinant Human Insulin Like Growth Factor-II is fully biologically active when compared to standard. The ED50, calculated by the dose-dependent induction of MCF-7 cell proliferation, is 0.85 ng/ml.

Accession No.: P01344

MW: 7505 Da

Sequence:
AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE

Purity:
Purity > 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 50 ug of lyophilized protein. Reconstitute with 0.5 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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