Ruthenium Red

Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+release from ryanodine-sensitive intracellular stores in skeletal and cardiac muscle (Kis = 16 nM - 5.9 μM, depending on Ca2+ concentration). Additionally, ruthenium red binds to anionic sites of cellular components, predominantly to surface glycoconjugates, and can be used as a marker of negative binding sites related to cellular transport, barrier, or receptor functions.

Application: Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.

Synonyms: Ammoniated ruthenium oxychloride, Ruthenium (III) Chloride Oxide Ammoniated; RR

Molecular Weight : 786.35
Molecular Formula : [(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
Storage : RT
Solubility : Soluble in NH4OH, and water (10 mg/ml)
Appearance Form : Solid
Appearance Color : Dark Purple
Brand Name : bioPLUS™