12 Lipoxygenase polyclonal, anti-human

Quantity: 100 µg

Background:
ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNAArachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12(S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.

Description:
Rabbit IgG polyclonal antibody for Arachidonate 12-lipoxygenase, 12S-type (ALOX12) detection. Tested with WB in Human.

Synonyms:
12 LOX antibody, 12(S) lipoxygenase antibody, 12S LOX antibody, 12S-lipoxygenase antibody, 12S-LOX antibody, 12S-type antibody, ALOX12 antibody, Alox12L antibody, Alox15 antibody, Arachidonate 12 lipoxygenase antibody, Arachidonate 12 lipoxygenase, 12S type antibody, Arachidonate 12 lipoxygenase, leukocyte type antibody, Arachidonate 12-lipoxygenase antibody, EC1.13.11.31 antibody, LOG12 antibody, LOX12_HUMAN antibody, Platelet type lipoxygenase 12 antibody, Platelet-type lipoxygenase 12 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ALOX12(609-628aa HHKEKYFSGPKPKAVLNQFR), different from the related rat sequence by four amino acids, and from the related mouse sequence by five amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.