5-Lipoxygenase (Ser523) polyclonal, anti-human, rat

Protein Family: Enzymes

Pathway and Disease: Lipid Metabolism, Infectious Diseases

Description:
Arachidonate 5-lipoxygenase (5-Lipoxygenase) catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes. Serine phosphorylation by MAPKAPK2 is stimulated by arachidonic acid. Phosphorylation on Ser-523 by PKA has an inhibitory effect.

Alternate Names: Arachidonate 5-lipoxygenase, 5-LO, 5-lipoxygenase, ALOX5, LOG5

Application Notes: E: 1:1,000; WB: 1:1,000

Accession No.: P09917

Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser523 of human 5-lipoxygenase (5-LO).

Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.