5'-nucleotidase cytosolic II polyclonal, anti-human, mouse, bovine

Protein Family: Cellular Antigens, Enzymes

Pathway and Disease: Metabolic Disorders, Nucleotide Metabolism

Description:
The 5'-nucleotidase cytosolic II (NT5C2) has a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. NT5C2 preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides. Aberration in NT5C2 is related to the urate production in hyperuricemia and gout.

Alternate Names: Cytosolic purine 5'-nucleotidase, 5'-nucleotidase cytosolic II, NT5C2, NT5B, NT5CP, PNT5

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P49902

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NT5C2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.