53BP1 (Phospho-Ser25) polyclonal, anti-human, mouse, rat

Specificity:
53BP1 (Phospho-Ser25) Antibody detects endogenous levels of 53BP1 only when phosphorylated at Ser25.

Synonyms: p53-binding protein 1, P531, TP53B, TP53BP1, TRP53BP1, Tumor suppressor p53-binding protein 1

Immunogen:
The antiserum was produced against synthesized peptide derived from human 53BP1 around the phosphorylation site of Ser25.

Immunogen Sequence:
10-59

Target Modification: Phospho

Modification Sites: H:S25 M:S25 R:S30

MW (kDa): 213 kDa

NCBI Gene Symbol: TP53BP1

Database Links:
Gene ID: 7158
Swiss Prot No.: Q12888
OMIM No.: 605230
Unigene No.: Hs.440968

Application Dilutions: IHC: 1:50~1:100, IF: 1:100~1:500, ELISA: 1:1000

Purification:
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Physical Format:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/ml

Storage: Stable at -20°C for at least 1 year.