8-OHdG polyclonal biotin, anti-human, mouse, rat

Protein Family: Cellular Antigens

Pathway and Disease: Cancers, Replication and Repair, Signaling Molecules and Interaction

Description:
8-hydroxydeoxyguanosine (8-OHdG) is a modified base indicative of DNA damage associated with mutagenesis and carcinogenesis. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions such as Alzheimer’s disease. Product Cat. No. 252514 is the biotin conjugate of Cat. No. 251640.

Alternate Names: 8-OHdG, 8-oxoguanine, 8-hydroxy-2-deoxyguanine, 8-oxyguanosine, 7, 8-Dihydro-8-oxo-2'-deoxyguanosine, 7, 8-Dihydro-8-oxodeoxyguanosine, 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxydeoxyguanosine, 8-Oxo-2'-deoxyguanosine, 8-Oxo-7, 8-dihydro-2'-deoxyguanosine, 8-Oxo-7, 8-dihydrodeoxyguanosine, 8-Oxo-dG

Application Notes: Product Cat. No. 252514 is the biotin conjugate of Cat. No. 251640. E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: CAS 88847-89-6

Antigen: KLH-conjugated 8-OHdG.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.