A Blood Group antigen (clone BRIC 145) Affinity Purified, anti-human
€304.00
In stock
SKU
ARP-08-9434-2
Catalog Number: 08-9434-2
Size: 50 µg
Isotype: Mouse IgG1, kappa light chain
Size: 50 µg
Isotype: Mouse IgG1, kappa light chain
Decription:
Mouse monoclonal antibody to human Blood Group A Antigen Affinity purified. The histo-blood group A antigen is defined by the carbohydrate structure at the non-reducing termini of oligosaccharide chains of glycoproteins and glycolipids. Carbohydrate chains are synthesized by the action of alpha -Nacetyl-D-galactosaminyl-transferase, which catalyzes the transfer of GalNAc monosaccharide to an acceptor substrate, the H antigen. The structure of the A antigen is : GalNAc (alpha 1-3)Gal(beta 1-3)GlcNAc-R-Fuc (alpha 1-2). The A antigen is divided into 2 main subgroups, A1 and A.
Synonyms: Blood Group A antigen
Clone: BRIC 145
Isotype: Mouse IgG1, kappa light chain
Immunogen: Blood Group A antigen was made in response to immunisation with A active ovarian cyst glycoprotein.
Reactivity: human
Form: Affinity purified, in 0.1 M glycine buffer, 1 M Tris buffer, pH 7.4, sterile filtered
Applications: Flow Cytometry, Indirect Immunofluorescence, Immunoblotting, Immunocytochemical techniques.
Working Dilution: Optimal dilution should be performed by user
Storage: 2-8C for immediate use, or at -20C (aliquot)
References:
1. Curtis B.R et al. (2000) Blood group A and B antigens are strongly expressed on platelets of some individuals. Blood 96: 1574-1581.
2. Achermann F.J. et al. (2005) Soluble type A substance in fresh-frozen plasma as a function of ABO and Secretor genotypes and Lewis phenotype. Transfusion and Apheresis Science 32 255-262.
3. Anstee DJ, Cartron J-P. (1997) Towards an understanding of the red cell surface. In:Garratty G, ed. Applications of molecular biology to transfusion medicine:17-49. American Association of Blood Banks, Bethesda, MD.
4. Daniels G. (2002) Human blood groups (second Ed.). Blackwell Science Ltd , Oxford , UK .
5. Issitt PD, Anstee DJ (1998) Applied blood group serology. 4th edn. Montgomery Scientific Publications, Durham, NC.
6. Mollison PL, Engelfriet CP, Contreras M. (1997) Blood Transfusion in clinical medicine. 10th edn. Blackwell Science, Oxford.
7. Reid ME, Lomas-Francis C. (1997) The blood group antigen facts book. Academic Press, London.
Mouse monoclonal antibody to human Blood Group A Antigen Affinity purified. The histo-blood group A antigen is defined by the carbohydrate structure at the non-reducing termini of oligosaccharide chains of glycoproteins and glycolipids. Carbohydrate chains are synthesized by the action of alpha -Nacetyl-D-galactosaminyl-transferase, which catalyzes the transfer of GalNAc monosaccharide to an acceptor substrate, the H antigen. The structure of the A antigen is : GalNAc (alpha 1-3)Gal(beta 1-3)GlcNAc-R-Fuc (alpha 1-2). The A antigen is divided into 2 main subgroups, A1 and A.
Synonyms: Blood Group A antigen
Clone: BRIC 145
Isotype: Mouse IgG1, kappa light chain
Immunogen: Blood Group A antigen was made in response to immunisation with A active ovarian cyst glycoprotein.
Reactivity: human
Form: Affinity purified, in 0.1 M glycine buffer, 1 M Tris buffer, pH 7.4, sterile filtered
Applications: Flow Cytometry, Indirect Immunofluorescence, Immunoblotting, Immunocytochemical techniques.
Working Dilution: Optimal dilution should be performed by user
Storage: 2-8C for immediate use, or at -20C (aliquot)
References:
1. Curtis B.R et al. (2000) Blood group A and B antigens are strongly expressed on platelets of some individuals. Blood 96: 1574-1581.
2. Achermann F.J. et al. (2005) Soluble type A substance in fresh-frozen plasma as a function of ABO and Secretor genotypes and Lewis phenotype. Transfusion and Apheresis Science 32 255-262.
3. Anstee DJ, Cartron J-P. (1997) Towards an understanding of the red cell surface. In:Garratty G, ed. Applications of molecular biology to transfusion medicine:17-49. American Association of Blood Banks, Bethesda, MD.
4. Daniels G. (2002) Human blood groups (second Ed.). Blackwell Science Ltd , Oxford , UK .
5. Issitt PD, Anstee DJ (1998) Applied blood group serology. 4th edn. Montgomery Scientific Publications, Durham, NC.
6. Mollison PL, Engelfriet CP, Contreras M. (1997) Blood Transfusion in clinical medicine. 10th edn. Blackwell Science, Oxford.
7. Reid ME, Lomas-Francis C. (1997) The blood group antigen facts book. Academic Press, London.
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