α-SMA (clone ), anti-human, mouse, rat, zebra fish
€428.00
In stock
SKU
BS9908M
Background:
Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Alternative Name:
ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, alpha-SMA, a-SMA, aSMA, SMA-alpha,
Application Dilution: WB: 1:1000-1:5000, IHC: 1:50-1:200, FC: 1:50-1:100
Specificity: This antibody detects endogenous levels of α-SMA and does not cross-react with related proteins.
Immunogen:
Recombinant antibody.
MW: ~ 42 kDa
Swis Prot.: P62736
Purification & Purity:
Protein A affinity purified
Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Alternative Name:
ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, alpha-SMA, a-SMA, aSMA, SMA-alpha,
Application Dilution: WB: 1:1000-1:5000, IHC: 1:50-1:200, FC: 1:50-1:100
Specificity: This antibody detects endogenous levels of α-SMA and does not cross-react with related proteins.
Immunogen:
Recombinant antibody.
MW: ~ 42 kDa
Swis Prot.: P62736
Purification & Purity:
Protein A affinity purified
Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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