AAK1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7861b
Background:
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
Other Names:
AP2-associated protein kinase 1, Adaptor-associated kinase 1, AAK1, KIAA1048
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7861b was selected from the C-term region of human AAK1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: AAK1
Gene ID: 22848
Primary Accession: Q2M2I8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
Other Names:
AP2-associated protein kinase 1, Adaptor-associated kinase 1, AAK1, KIAA1048
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7861b was selected from the C-term region of human AAK1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: AAK1
Gene ID: 22848
Primary Accession: Q2M2I8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review