AAT (clone 2B12), anti-human, mouse
€394.00
In stock
SKU
252890
Catalog Nr.: 252890
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB
Protein Family: Enzymes, Peptidases
Pathway and Disease: Immune System; Folding, Sorting, and Degradation
Description:
AAT (Alpha-1-antitrypsin) is an inhibitor of serine proteases. Although AAT's primary target is elastase, the enzyme has also a moderate affinity for plasmin and thrombin. AAT inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. AAT deficiency is related to emphysema and liver disease.
Alternate Names: Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, SERPINA1, AAT, PI
Application Notes: E: 1:10000; WB: 1:500-1:2000
Accession No.: P01009
Antigen: Purified recombinant fragment of human AAT expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System; Folding, Sorting, and Degradation
Description:
AAT (Alpha-1-antitrypsin) is an inhibitor of serine proteases. Although AAT's primary target is elastase, the enzyme has also a moderate affinity for plasmin and thrombin. AAT inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. AAT deficiency is related to emphysema and liver disease.
Alternate Names: Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, SERPINA1, AAT, PI
Application Notes: E: 1:10000; WB: 1:500-1:2000
Accession No.: P01009
Antigen: Purified recombinant fragment of human AAT expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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