ABCA4 (clone 3F4), anti-human, mouse, rat
€418.00
In stock
SKU
253108
Catalog Nr.: 253108
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC
Protein Family: Transporters
Pathway and Disease: Membrane Transport
Description:
ATP-binding cassette sub-family A member 4 (Retinal-specific ATP-binding cassette transporter, ABCA4, Rim Protein) facilitates the transfer of N-retinyl-phosphatidylethanolamine (NR-PE), a covalent adduct of all-trans retinaldehyde (ATR) with phosphatidylethanolamine (PE), to the cytoplasmic surface of rod photoreceptors. ABCA4 functions as a flippase, which is a transmembrane protein that “flips” its conformation to transport materials across a membrane.
Alternate Names: Retinal-specific ATP-binding cassette transporter, ATP-binding cassette sub-family A member 4, RIM ABC transporter, RIM protein, RmP, Abca4, Abcr
Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:100
Accession No.: O35600
Antigen: Partially purified bovine 220-kDa disc rim protein.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Membrane Transport
Description:
ATP-binding cassette sub-family A member 4 (Retinal-specific ATP-binding cassette transporter, ABCA4, Rim Protein) facilitates the transfer of N-retinyl-phosphatidylethanolamine (NR-PE), a covalent adduct of all-trans retinaldehyde (ATR) with phosphatidylethanolamine (PE), to the cytoplasmic surface of rod photoreceptors. ABCA4 functions as a flippase, which is a transmembrane protein that “flips” its conformation to transport materials across a membrane.
Alternate Names: Retinal-specific ATP-binding cassette transporter, ATP-binding cassette sub-family A member 4, RIM ABC transporter, RIM protein, RmP, Abca4, Abcr
Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:100
Accession No.: O35600
Antigen: Partially purified bovine 220-kDa disc rim protein.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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