ABCB11 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71760
Background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
Alternative Name:
BSEP, PGY4, SPGP, ABC16, BRIC2, PFIC2, PFIC-2,
Application Dilution: WB : 1:500 - 1:2000
Specificity: ABCB11 polyclonal antibody detects endogenous levels of ABCB11 protein.
Immunogen:
Recombinant protein of human ABCB11
MW: Predicted band size: 146 kDa, Observed band size: Refer to Figures
Swis Prot.: O95342
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
Alternative Name:
BSEP, PGY4, SPGP, ABC16, BRIC2, PFIC2, PFIC-2,
Application Dilution: WB : 1:500 - 1:2000
Specificity: ABCB11 polyclonal antibody detects endogenous levels of ABCB11 protein.
Immunogen:
Recombinant protein of human ABCB11
MW: Predicted band size: 146 kDa, Observed band size: Refer to Figures
Swis Prot.: O95342
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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