ABCB7 Antibody (C-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP6114a
Background:
The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.
Other Names: ATP-binding cassette sub-family B member 7, mitochondrial, ATP-binding cassette transporter 7, ABC transporter 7 protein, ABCB7, ABC7
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6114a was selected from the C-term region of human ABCB7 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: O75027
Other Accession: NP_004290
Gene ID: 22
Gene Name: ABCB7 (HGNC:48)
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Allikmets, R., et al., Hum. Mol. Genet. 8(5):743-749 (1999).Csere, P., et al., FEBS Lett. 441(2):266-270 (1998).Mao, M., et al., Proc. Natl. Acad. Sci. U.S.A. 95(14):8175-8180 (1998).Shimada, Y., et al., J. Hum. Genet. 43(2):115-122 (1998).Savary, S., et al., Genomics 41(2):275-278 (1997).
The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.
Other Names: ATP-binding cassette sub-family B member 7, mitochondrial, ATP-binding cassette transporter 7, ABC transporter 7 protein, ABCB7, ABC7
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6114a was selected from the C-term region of human ABCB7 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: O75027
Other Accession: NP_004290
Gene ID: 22
Gene Name: ABCB7 (HGNC:48)
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Allikmets, R., et al., Hum. Mol. Genet. 8(5):743-749 (1999).Csere, P., et al., FEBS Lett. 441(2):266-270 (1998).Mao, M., et al., Proc. Natl. Acad. Sci. U.S.A. 95(14):8175-8180 (1998).Shimada, Y., et al., J. Hum. Genet. 43(2):115-122 (1998).Savary, S., et al., Genomics 41(2):275-278 (1997).
| Is Featured? | No |
|---|
Write Your Own Review